Disease: Achondroplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
SLC20A1 Q8WUM9 solute carrier family 20 member 1 Transporter 6.7E-02 0.582 0.577
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
MSX1 P28360 msh homeobox 1 Transcription factor 0.17 0.525 0.731
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FGF1 P05230 fibroblast growth factor 1 Signaling 0.44 0.507 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
EDN3 P14138 endothelin 3 Signaling 2.5E-02 0.608 0.577
DCN P07585 decorin 0.31 0.457 0.808